Modders have successfully enabled NVIDIA's DLSS Multi Frame Generation on older GPU generations—RTX 40, RTX 30, and RTX 20 series—through various native implementations, though compatibility remains experimental and subject to breakage from driver or runtime updates.
Modders have successfully enabled DLSS Multi Frame Generation, a feature previously exclusive to RTX 40-series GPUs, on older RTX 30-series Ampere graphics cards through modification.